Transsphenoidal hypophysectomy as a treatment for Rathke's cleft cyst in a dog

The objective of the study was to describe clinical, imaging, surgical and histological findings in a dog with Rathke's cleft cyst pituitary gland. A 6-year-old, female, neutered Staffordshire bull terrier presented an acute onset abnormal behaviour. Magnetic resonance imaging skull showed mass 12.9 mm (height) × 8.8 (width) 10.2 (length) height/brain area value 0.73 (reference <0.31). were suggestive apoplexy or neoplasia. Transsphenoidal hypophysectomy performed cystic removed. Histopathology revealed lined by layer pseudo-stratified ciliated columnar epithelial cells mucin-secreting goblet remnant tissue positive immunostaining against adrenocorticotropic hormone, alpha melanocyte growth hormone periphery. should be included differential diagnosis masses dog, transsphenoidal is effective treatment.